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lucasa
Level 1
Join date: Jun 2004
Location: Illinois, USA
Posts: 1648
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ALA: Anabolic Fat Loss?
by David Barr
04/05/06
If you've added or lost a pound in a couple of months after beginning use of a supplement, there's just no way to say that it was the supplement that caused the change. It's quite possibly the result of any of a million lifestyle alterations that are beyond our control.
This one sentence makes the entire article worth it, IMO. Now, I'm gonna go eat my cheerios because they lower my cholesterol. |
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richieY2K
Level 4
Join date: Apr 2005
Location:
Posts: 120
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just EXCELLENT David.
You're (not "your" LOL) providing exactly the kind of critical thinking combined with background that is of immense help to us.
Did I mention OUTSTANDING?
Richard |
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Nick Radonjic
Level 0
Join date: Aug 2004
Location: Illinois, USA
Posts: 196
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At what dosages are these positive attributes of decreasing bodyfat, increasing muscle mass, etc. alleged to be achieved? The only reason I have been using it is because of the contention that it helps with the activation and circulation of other anti-oxidants.
Nick |
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Dr. E. Nigma
Level 0
Join date: May 2004
Location:
Posts: 1172
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Another 'four star' Barrticle from Dave "Dogma Destroyer" Barr. LOL
Have they tested ALA with Pop-Tarts? That is where the magic lies my friend.
Oh, I almost forgot, congratulations Canada on your National Igloo and adopting the 24hour clock. LMAO
Thanks Dave, this article was exactly what I have been waiting for. |
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Miserere
Level 2
Join date: Jun 2005
Location: Massachusetts, USA
Posts: 3041
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I was wondering when you'd get another article on the Nation, Dave. I always enjoy them.
As soon as I have some time I'll read it, but I'm sure it will be exactly what I was waiting for :-)
PS: What's that about the igloos?? |
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patrick123
Level 0
Join date: Feb 2006
Location:
Posts: 14
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David...is there a diference between ALA and it R-ALA?
I found no mention or differentiation between them in the studies.
Thanks |
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keninottawa
Level 0
Join date: Jan 2006
Location:
Posts: 23
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Question: I'm currently taking 400mg of R-isomer ALA every day because I thought the supplement would help in the long-term protection of insulin sensitivity on a high-calorie diet and that it would lessen the insulin spikes that I would get from higher-carb meals.
Am I wasting my money? |
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Ruggerlife
Level 4
Join date: Aug 2005
Location: Ontario, CAN
Posts: 2666
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T-Nation wrote:
<p class="email">2) This is only the second exercise study in which I've seen pro-oxidative damage, and both involve the same mechanism of antioxidant action.</p>
...
<p>What's disturbing is that both exercise studies showing the use of antioxidants causing oxidative damage involved the same type of supplement action. The research with resistance training and humans used vitamin C and N-Acetyl Cysteine (3), while the rodent running study used ALA –
Dave,
Has there been any theories evolving that are worth noting as to why this occurs/which antioxidents may cause it/is it a dosing issue/ etc...
If so take this as a hint for your next article- Antioxident Research review by Dave Barr of course to make the title interesting it'll be called Antioxidents - Hypertrophy or Death?
Enjoyed the article...It's about time! :)
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Need4Speed
Level 4
Join date: Dec 2004
Location: Washington, USA
Posts: 1750
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Dave, I don't have time to read the whole article, so I was just wondering if you could tell me how big I can get on ALA? |
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canada
Level 2
Join date: Aug 2005
Location: Newfoundland, CAN
Posts: 211
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Is it just me? These supplment articles are boring has hell. Of course, anyone can see the advantages/convenience of protein powders, creatine, fish oil etc but these for lack of a better work exotic supplments, who cares!!
Training and good eating habits! That's what i want to read.
That and TC's articles which are pretty damn cool. |
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jsbrook
Level 5
Join date: Mar 2005
Location: New York, USA
Posts: 9442
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Another article where Dave's raised the barr. (yuk yuk). Do you know if there's similar evidence questioning the efficacy of carnitine (ALCAR)? The combination of ALA and ALCAR was once highly touted and maybe is in some circles. |
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wyrd1
Level 3
Join date: Feb 2006
Location: Idaho, USA
Posts: 136
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Our bodies are bent on survival, which usually means preserving energy levels at all costs. Without energy, we die (duh). So if our cells sense that we're low on energy, the last thing it wants to do is create more metabolically active tissue (muscle). Don't forget that muscle not only takes a lot of energy to synthesize, but also to maintain, which is why it requires so much food to cause hypertrophy.
This one paragraph was worth reading the whole fraggin article. It explains why it's easy to lose fat is the summer, why I can gain bulk easy, why people gain a little fat while "bulking" and why my younger brother can eat so much and still look like the guy in "Fight Club" all the girls seem to ogle.
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hockechamp14
Level 4
Join date: Mar 2005
Location: Connecticut, USA
Posts: 2302
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Thank you for posting this... I think my step mom who has MS takes it, I'll talk to her about taking it and how it is undetermined to cause an effect at this point. |
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yorik
Level 4
Join date: Feb 2003
Location: Florida, USA
Posts: 1377
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As I understand it, ALA is a symmetric molecule and can exist with either a right-hand "twist" or a left-handed one and still be called ALA, hence there are two "isomers" r- and s- ALA.
Supposedly, a standard bottle of ALA contains both s-ALA and r-ALA in roughly equal amounts, since laboratory processes create an equal amount of both isomers. Cellular processes of creating ALA only create r-ALA. Again, "supposedly". The theory being that only r-ALA is effective in the body.
I've seen references to studies that supposedly demonstrated a significant difference between s-ALA and r-ALA, and attributed the "bad" effects to s-ALA. In fact, the claim is that s-ALA will actually cancel out the r-. I'll see if I can find the references again.
Since I got a lot of this info from a site that sells r-ALA, I'd like to see some independent verification. r-ALA costs a lot more than plain ALA. Is any of it worth it? |
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David Barr
Contributor
Join date: Jan 2004
Location: California, USA
Posts: 2492
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Nick Radonjic wrote:
At what dosages are these positive attributes of decreasing bodyfat, increasing muscle mass, etc. alleged to be achieved? The only reason I have been using it is because of the contention that it helps with the activation and circulation of other anti-oxidants.
Nick
It's anywhere from 100mg to 1000g, with an average around 500mg/d.
I've noticed (whatever that means) an unfortunate drop in blood sugar at 200mg (racemic) PWO. |
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David Barr
Contributor
Join date: Jan 2004
Location: California, USA
Posts: 2492
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Dr. Ryan wrote:
Have they tested ALA with Pop-Tarts? That is where the magic lies my friend.
There are no clinical data, but anecdotal evidence suggests that the effects of this combo are on par with 1g of test/week.
Oh, I almost forgot, congratulations Canada on your National Igloo and adopting the 24hour clock. LMAO
Thanks, we are quite proud!
Thanks Dave, this article was exactly what I have been waiting for.
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IamMarqaos
Level 3
Join date: Sep 2004
Location: California, USA
Posts: 813
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canada wrote:
Is it just me? These supplment articles are boring has hell. Of course, anyone can see the advantages/convenience of protein powders, creatine, fish oil etc but these for lack of a better work exotic supplments, who cares!!
Training and good eating habits! That's what i want to read.
That and TC's articles which are pretty damn cool.
Yep..it is just you :) |
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FairDo
Level 0
Join date: Feb 2004
Location: Poland
Posts: 204
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jsbrook wrote:
Another article where Dave's raised the barr. (yuk yuk). Do you know if there's similar evidence questioning the efficacy of carnitine (ALCAR)? .
I thought that everybody already knows for a long time that carnitine is a dead horse!
Actually, there's very few supplements that are "dead-er" than creatine
:) |
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David Barr
Contributor
Join date: Jan 2004
Location: California, USA
Posts: 2492
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Miserere wrote:
I was wondering when you'd get another article on the Nation, Dave. I always enjoy them.
As soon as I have some time I'll read it, but I'm sure it will be exactly what I was waiting for :-)
PS: What's that about the igloos??
Thanks for the comments!
We are quite happy with our igloos in Canada, but we are concerned about global warming.
I'll see if I can dig up the video link.
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David Barr
Contributor
Join date: Jan 2004
Location: California, USA
Posts: 2492
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hockechamp14 wrote:
Thank you for posting this... I think my step mom who has MS takes it, I'll talk to her about taking it and how it is undetermined to cause an effect at this point.
Before you do that, let's be sure to look at the health benefits of ALA in disease states. This article really focused on performance and body composition, but medical use has a whole other story. |
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ScottL
Level 3
Join date: Oct 2002
Location: Pennsylvania, USA
Posts: 537
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jsbrook wrote:
Another article where Dave's raised the barr. (yuk yuk). Do you know if there's similar evidence questioning the efficacy of carnitine (ALCAR)? The combination of ALA and ALCAR was once highly touted and maybe is in some circles.
The work on ALA (might have been R-ala) and ALCAR was done by Lester Packer (see refs above) a big name in research. It is rat work and so the usual caveats apply, but has not been questioned.
The health benefits of ALA/R-ala have not been questioned. See PDR for supps:
http://www.pdrhealth.com/.../alp_0159.shtml
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canada
Level 2
Join date: Aug 2005
Location: Newfoundland, CAN
Posts: 211
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IamMarqaos wrote:
canada wrote:
Is it just me? These supplment articles are boring has hell. Of course, anyone can see the advantages/convenience of protein powders, creatine, fish oil etc but these for lack of a better work exotic supplments, who cares!!
Training and good eating habits! That's what i want to read.
That and TC's articles which are pretty damn cool.
Yep..it is just you :)
Damn! Just me..? Goes and hide in his corner. :-)
I guess some folks like this stuff just not my cup of tea. |
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Bauer97
Level 4
Join date: Aug 2005
Location: Pennsylvania, USA
Posts: 2638
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canada wrote:
IamMarqaos wrote:
canada wrote:
Is it just me? These supplment articles are boring has hell. Of course, anyone can see the advantages/convenience of protein powders, creatine, fish oil etc but these for lack of a better work exotic supplments, who cares!!
Training and good eating habits! That's what i want to read.
That and TC's articles which are pretty damn cool.
Yep..it is just you :)
Damn! Just me..? Goes and hide in his corner. :-)
I guess some folks like this stuff just not my cup of tea.
Yeah, just you.
There is more "training and good eating habits" info on this site than I could possibly process into my mind in a year.
I like to learn, objectively and in depth, about something entirely different once in a while. And, for the record, there was plenty of information in the article that wasn't directly about ALA, but specific aspects of human performance.
Nice work as always DB, hope to see more in the near future. |
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pkradgreek
Level 5
Join date: Oct 2002
Location: New York, USA
Posts: 1344
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so is there any point in time you could potentially use R-ALA in an effective manner for whatever reason?
examples: during a protein carb after fasting state meal like breakfast? When eating cheat meals with high amounts of insulin prodrucing food combinations?
also can we address other similar compounds like 4-hydroxyisoleucine, cinnulin, or banaba extract?
laters pk |
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