| Estradiol: Why You Should Care |
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HiredGun
Level 0
Join date: Feb 2010
Location: Colorado, USA
Posts: 31
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I suppose that because my numbers for Total T, Free T and E2 are all high I might simply reduce the weekly T input and resolve my out of balance E2 that way.
Waiting for KSman to give me his opinion. |
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KSman
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Join date: Aug 2006
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Posts: 2635
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I think that you should go towards serum E2=22pg/ml then based on how you feel, do what you are motivated to do from there. You can always go back to where you were. Why be a slave to a whim of a doctor who does not understand this issue. |
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HiredGun
Level 0
Join date: Feb 2010
Location: Colorado, USA
Posts: 31
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KSman wrote:
I think that you should go towards serum E2=22pg/ml then based on how you feel, do what you are motivated to do from there. You can always go back to where you were. Why be a slave to a whim of a doctor who does not understand this issue.
Oh that is not even under consideration. See my follow up post just above yours, I was wondering if I should simply back off the T quantity per week and see if that brings E2, Free-T and Total T down. Do you think my situation is that simple ?
I also need to get on the monthly self lab tests using the post I got a ways back in this thread.
New Anastrozole pills just arrived. I got a lot. These are different - blue and pink CMP Anastrozole 0.25 MG Cap. Says 'Take 1 capsule by mouth daily'.
Now this is not the original doctor, that one imploded when they got raided for pain clinics last week. So this number means nothing. However if I was at .5 mg per week this is suggesting 1.75 per week and seems spot on since I have almost double E2 rule of thumb would suggest going to just under double the Anastrozole.. so .5 X 2 = 1.0 per week. so .25 every other day would be 1.0 per week.
This Anastrozole is compounded and not name brand. Does that throw off the calculation at all ? I bet the answer is we just make the adjustment and go get the bloodwork done to be sure.
Thanks |
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HiredGun
Level 0
Join date: Feb 2010
Location: Colorado, USA
Posts: 31
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Wow GeoBob's free test blows mine away. Does correcting E2 help with free test ? |
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KSman
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Join date: Aug 2006
Location:
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Yes, less E2 should lead to less SHBG bound T and more FT. In any case, less E2 interfering with T is the major effect. My FT is >49 with LabCorp. That is the upper reporting limit. FT=38.6 is not really that high when you consider youthful non-age adjusted ranges. When I turned 60, suddenly my FT range limit became something bogus like 28. |
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HiredGun
Level 0
Join date: Feb 2010
Location: Colorado, USA
Posts: 31
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KSman wrote:
Yes, less E2 should lead to less SHBG bound T and more FT. In any case, less E2 interfering with T is the major effect. My FT is >49 with LabCorp. That is the upper reporting limit. FT=38.6 is not really that high when you consider youthful non-age adjusted ranges. When I turned 60, suddenly my FT range limit became something bogus like 28.
Will I ever achieve his 'Free testosterone 266.7 pg/mL down from 273.8 six weeks ago. (range 50-210)' at age 46 ? Certainly I am putting enough T in, how the heck did he get 266 ?? |
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HiredGun
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Join date: Feb 2010
Location: Colorado, USA
Posts: 31
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Is Geobob's 266 incorrect ???
It depends on a man's age. The normal range of free testosterone is 1.0-5.0 ng/dl. However, a guy in his 20's may have levels around 41.0 pg/ml ( p grams/milliliter) while a gentleman in his 80's may have around 9.0 pg/ml -- and they would both be considered normal. |
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Chopperdog
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Join date: Dec 2009
Location:
Posts: 2
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1st post. I have been lurking and reading for awhile. I have been on TRT, 1st Androgel and now T injections. My doc is doing it, but is really not very knowledgeable. How do I find someone a little more familiar with these protocols. I have not been taking hCG or an E suppressor. |
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KSman
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Join date: Aug 2006
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Posts: 2635
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Chopperdog: Where are you located? Insurance or paying out of pocket? How long on A-gel and how long on Injections? What dose and frequency? Why did you quit A-gel? |
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Chopperdog
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Join date: Dec 2009
Location:
Posts: 2
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I am in Memphis. My insurance is a little funny. I have to pay out of pocket for a large part on the front end. I was on Androgel for about 6 months and quit for 6-9 months and then started again for 6 months or so. I found that the daily ritual of rubbing on the gel was inconvenient and I just did not see much difference. I also have a 9 year old and don't want to take a chance of getting it on him. It is just so much easier to get a T Cyp shot. I was getting a shot once a month and then just switched to a divided 2 week dose and now after rereading I think I need to go on an every week shot. I have known my doc for 30 years and we can have a very open conversation, I just think that this will probably take him out of his comfort zone and he will recommend an Endocrinology consult. If I have to go to someone else, I would just as soon get someone that knows what to do. Thx for any advice |
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